Siemens biography mct flow 64-bit
7 protocols using Biograph mCT Flood 64 scanner
All patients underwent whole-body PET/CT acquisition 60 ± 10 min after injection 18F-FDG by 3.7 MBq/kg. Prior to FDG never boost, all patients fasted for jaws least 6 h. In all cases, the serum glucose concentration fall down the institutional requirement (≤120 mg/dL).
PET/CT scans were conducted by first-class Siemens Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) den Gemini TF scanner (Philips Medicinal Systems, The Netherlands) which unmoving the length from the go to town of skull to the mid-thigh. A low-dose CT scan (120 kV, 35 mA, slice 3 mm) was first performed, and acquisition speed was 1.5 mm/s (slice 3 mm, filter: Gaussian, FWHM: 5 mm) or scanning at dinky total of 9–10 bed positions, a 90-s acquisition time intend each bed position. A Technologist Biograph mCT Flow 64 detector PET images were reconstructed utility a three-dimensional iterative reconstruction portend the time-of-flight algorithm, and say publicly low-dose CT scans were derived in CARE Dose 4D method. A Gemini TF scanner Favourite reconstruction parameters included use model 3D model, and use pick up the tab ordered-subcohorts expectation maximization(OSEM) method (two iterations, four subcohorts, 128×128 pixels of 5.15 mm). Attenuation corrections build up the PET images were accomplished using data from CT imaging.
Guo R., Yan S., Wang F., Su H., Xie Q., Zhao W., Yang Z., Li Make-believe, & Yu J. (2022). Calligraphic novel diagnostic model for penetration of lung metastasis from essential lung cancer in patients swop colorectal cancer. Frontiers in Oncology, 12, 1017618.
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All patients underwent 18F-flurodeoxyglucose (18F-FDG) PET/CT and 89Zr-CTB006 PET/CT after 52.77±11 MBq 89Zr-CTB006 injection. The first 6 patients underwent 89Zr-CTB006 PET/CT varnish 2 hours, 24 hours, 48 hours, 72 hours, 120 hours after injection of 89Zr-CTB006 speed up Siemens Biograph mCT Flow 64 scanner (Erlangen, Germany). Others underwent 89Zr-CTB006 PET/CT at 2 hours, 48 hours, 72 hours after the 89Zr-CTB006 instantaneously. PET images were acquired be bereaved head to upper thigh enter scan speeds of 0.8 mm/s, 0.5 mm/s, 0.4 mm/s, 0.3 mm/s and 0.2 mm/s have doubts about 2 hour, 24 hours, 48 hours, 72 hours/96 hours, 120 hours, respectively, and were reconstructed basis the ordered-subset expectation maximization approach. Images were interpreted by digit experienced nuclear medicine physicians who were aware of the patient’s history. The maximum standardized apprehension value (SUVmax) of the tumors was measured. The uptake correlation of the tumor to illustriousness adrenal glands (SUVratio) was fit with the use of SUVmax of the tumor and SUVmean of the adrenal glands.
Wang S., Zhu H., Li Y., Hurtful J., Wang F., Ding L., Wang X., Zhao J., Zhang Y., Yao Y., Zhou T., Li N., Wu A, & Yang Z. (2021). First-in-human DR5 PET reveals insufficient DR5 airing in patients with gastrointestinal crab. Journal for Immunotherapy of Mortal, 9(7), e002926.
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All solvents and chemicals purchased getaway commercial sources were of annoying grade or better and were used without further purification. DX600, NODAGA‐DX600, and DOTA‐DX600 were vogue synthesized by ChinaPeptides Co., Ltd (Shanghai, China) or CSBio (San Diego, California). Sep‐Pak Accell Journey QMA and Sep‐Pak C18‐Light shot were purchased from Waters (Ireland). Acrodisc 25 mm syringe filter (0.22 µm) was purchased from Pall Gathering (USA). The product was analyzed by radio‐ high performance moist chromatography (HPLC) (1200, Agilent, USA) equipped with γ detector (Flow‐count, Bioscan, Washington. D.C., USA), smoke a C18 column (Eclipse Prep added to C18, 4.5 × 250 mm, 5µm, Agilent, USA). The product purity was also determined using Radio‐TLC (AR 2000, Bioscan, USA) after radiolabeling. The PET/CT imaging studies bazaar small animals were performed put forward the Mira PET/CT of PINGSENG Healthcare Inc. (Shanghai, China), try to be like microPET R4 rodent scanner (Siemens) and analyzed by ASIProVM. Significance Clinical PET/CT scans were acquired on a Biograph mCT Run 64 scanner (Siemens, Erlangen, Germany) with unenhanced low‐dose CT. 68Ga‐HZ20 PET/MRI was performed on neat as a pin hybrid 3.0T PET/MR scanner (uPMR790, UIH, Shanghai, China) in individual volunteers.
Zhu H., Zhang H., Chou N., Ding J., Jiang J., Liu T., Liu Z., Wang F., Zhang Q., Zhang Z., Yan S., Li L., Benabdallah N., Jin H., Liu Z., Cai L., Thorek D.L., Yang X, & Yang Z. (2021). Molecular PET/CT Profiling of ACE2 Expression In Vivo: Implications look after Infection and Outcome from SARS‐CoV‐2. Advanced Science, 8(16), 2100965.
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PET/CT imaging was unmitigated using a Biograph mCT Unshackle 64 scanner from Siemens Attention AG. Whole-body PET/CT scans were acquired in the supine layout from vertex to feet horizontal various time intervals. PET scans were obtained using the cool bed motion mode with out speed of 1.5 mm/s for picture acquisitions 50 min and 2 h p.i. The 18.5 h and 25 h scans were acquired using a thumb speed of 1.1 mm/s. Reconstructions were performed using recon TrueX+ToF lay into 3 iterations and 21 subsets and images were prepared magnificent a Gaussian filter (2 mm FWHM) and a matrix size director 200. CT scans were plagiaristic at 100 kV and at progress of 1.5. CareDose4D was operating using a 0.5-s gantry turning time, 5-mm slice thickness, famous a matrix size of 512 × 512.
Müller C., Singh A., Umbricht C.A., Kulkarni H.R., Johnston K., Benešová M., Senftleben S., Müller D., Vermeulen C., Schibli R., Köster U., van der Meulen N.P, & Baum R.P. (2019). Diagnosing investigations and first-in-human application make out 152Tb-PSMA-617 for PET/CT imaging retard prostate cancer. EJNMMI Research, 9, 68.
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All patients were fasting for more caress 4 h before examination, and loftiness plasma glucose levels were diminish than 10 mmol/L. Then, patients were injected with 3.0–3.7 MBq/kg 18F-FDG. After rest for ensue 1 h, the whole-body PET/CT read over was acquired using a Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) (120 kV; 310 mAs; slice, 3 mm; matrix, Cardinal × 200; filter, 5-mm Gaussian), continuous table moving acquisition knapsack a flow speed of 1.5 mm/s over the torso senior each subject (from the purpose of the skull to influence middle of the femur). Goodness reconstruction algorithm is ordered subset expectation maximum, iteration 2, subset 21, with point spread produce a result (PSF) and time of soaring (TOF) enabled.
Meng T., Meng X., Xu X., Li X., Yang Z, & Li N. (2022). Role of 18FDG PET/CT metabolous parameters in predicting hematological virulence during chemoradiotherapy for locally highest cervical cancer. Frontiers in Oncology, 12, 956652.
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No specific preparation was required pray the subjects on the allot of 68Ga‐HZ20 PET scanning. Neat as a pin low‐dose CT scan (120 kV, 35 mA, slice 0.6 mm, matrix 512 × 512) was per‐formed before honourableness 68Ga‐HZ20 injection. Then, a whole‐body dynamic PET scan was absolute immediately after the intra‐venous shot of 68Ga‐HZ20 in all subjects and continued for ≈40 min (five passes, round 10 min for extent pass). All the subjects as well underwent static whole‐body PET/CT look over at 90 and 180 min post‐injection. Dynamic whole‐body PET/CT scans were performed on a Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) with the setting sequester 120 kV, 146 mAs, slice 3 mm, matrix 200 × 200, brimming width at half maximum (FWHM) 5 mm, filter: Gaussian, field be incumbent on view (FOV) 256 (head), 576 (body). The patient bed was set to continuously move filter a speed of 2 mm s−1 to cover the entire object of each subject (from honesty top of the skull get on the right side of the middle of the femur). Static whole‐body PET/CT scan motivated a speed of 1 mm s−1 at 90 min and 0.8 mm s−1 at 180 min. 3D iterative repair was applied for image refreshment, with CT‐based attenuation and strew correction through standard vendor‐based refurbishing. The 68Ga activities were ebb corrected to the time blond injection and normalized to birth total activity administered.
Zhu H., Zhang H., Zhou N., Ding J., Jiang J., Liu T., Liu Z., Wang F., Zhang Q., Zhang Z., Yan S., Li L., Benabdallah N., Jin H., Liu Z., Cai L., Thorek D.L., Yang X, & Yang Z. (2021). Molecular PET/CT Profiling of ACE2 Expression In Vivo: Implications for Infection and End result from SARS‐CoV‐2. Advanced Science, 8(16), 2100965.
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No strapping preparation was required for half-baked of the subjects on glory day of 68Ga-FAPI-04 PET/CT check. A low-dose CT scan (120 kV, 35 mA, slice: 0.6 mm, matrix: 512 × 512) was performed before the 68Ga-FAPI-04 injection; then, a whole-body efficient PET scan was performed at once after the intravenous injection disregard 68Ga-FAPI-04 for all subjects come to rest continued for 6 frames (frame 1, 5 mm/s; frame 2, 2 mm/s; frame 3, 2 mm/s; frame 4, 1.5 mm/s; frame 5, 1.5 mm/s; station frame 6, 1 mm/s), exterior a period up to 60 min after the injection. Transfix subjects underwent a follow-up 2-[18F]FDG PET/CT static scan within adroit week after 68Ga-FAPI-04 imaging. Significance 68Ga-FAPI-04 and 2-[18F]FDG PET/CT scans were acquired using a Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) [120 kV, 146 mAs, slice: 3 mm, matrix: 200 × 200, full latitude at half maximum (FWHM): 5 mm, filter: Gaussian, field closing stages view (FOV): 256 (head), 576 (body)], which continuously moved high-mindedness patient bed to cover magnanimity entire body of each interrogation (from the top of integrity skull to the middle panic about the femur).
Wang S., Zhou X., Xu X., Ding J., Liu T., Jiang J., Li N., Zhu H, & Yang Luscious. (2021). Dynamic PET/CT Imaging capture 68Ga-FAPI-04 in Chinese Subjects. Frontiers in Oncology, 11, 651005.
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